Prosthetic Joint Infection Market Insights, Epidemiology and Market Forecast-2030
(Albany, US) DelveInsight launched a new report on Prosthetic Joint Infection Market Insights, Epidemiology and Market Forecast-2030
Some of the key facts of the report1. The total incident cases of Prosthetic Joint Infection in 7MM and China was 66,811 in 2017.2. The United States has the highest Prosthetic Joint Infection incident population with 35,653 cases in 2017.3. Among the European countries, Germany had the highest population of Prosthetic Joint Infection with 10,645 cases in 2017.4. Males are more prone to Prosthetic Joint Infection as compared to females.
Key benefits of the report1. Prosthetic Joint Infection market report covers a descriptive overview and comprehensive insight of the Prosthetic Joint Infection epidemiology and Prosthetic Joint Infection market in the 7 MM (the United States, EU5 (Germany, Spain, France, Italy, UK) & Japan.)2. Prosthetic Joint Infection market report provides insights into the current and emerging therapies.3. Prosthetic Joint Infection market report provides a global historical and forecasted market covering drug outreach in 7 MM.4. Prosthetic Joint Infection market report offers an edge that will help in developing business strategies by understanding trends shaping and driving the Prosthetic Joint Infection market.
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“Prosthetic Joint Infection Market Size in the 7MM and China was USD 61.63 million in 2017”.
The goals of PJI treatment are to eradicate the infection, restore the pain-free function of the infected joint, and minimize PJI-related morbidity and mortality for the patient. Unfortunately, not all of these goals may be possible for every patient. The challenge in the management of Prosthetic Joint Infection is the persistence of microorganisms on the implant surface in the form of biofilm. Understanding this ability, the phases of biofilm formation, antimicrobial susceptibility, and the limitations of host local immune response allows an individual choice of the most suitable Prosthetic Joint Infection treatment. The management of PJI almost always necessitates the need for surgical intervention and prolonged courses of intravenous or oral antimicrobial therapy.
Prosthetic Joint Infection usually requires combined medical-surgical strategies, including open or arthroscopic debridement without removal of the prosthesis, resection of the prosthesis with or without reimplantation either at the time of removal or delayed by weeks to months. Further arthrodesis, amputation, or antimicrobial suppression without surgery are also recommended.
Surgical strategies differ significantly worldwide; exchange procedures are the popular treatment modality in Northern America, whereas debridement and retention are more commonly performed in Europe. One-stage or direct arthroplasty exchange—preferred more in Europe; Two-stage arthroplasty exchange— preferred more in the US.
The generally used antibiotics are Cefazolin, Rifampin, Ciprofloxacin, Vancomycin, Penicillin, Ceftriaxone, Ampicillin, Gentamicin, Clindamycin, and others. These antibiotics may be used as monotherapy or combination therapy depending on the type of microorganisms. Rifampicin has excellent activity against Staphylococcal biofilms and is the mainstay of treatment in these infections, particularly with debridement and retention.
Fluoroquinolones, such as ciprofloxacin, are frequently used as companion drugs; however, fluoroquinolone resistance is increasing thus limiting the utility of this combination. Alternate companion drugs for rifampicin include fusidic acid, trimethoprim-sulfamethoxazole, minocycline, daptomycin, and linezolid.
Antimicrobial peptides are a new class of antibiotics with exciting features. They are highly active against a broad spectrum of microorganisms, highly selective toward microorganisms and not mammalian cells, present fast killing even at low concentrations and most importantly, they have a much lower tendency to induce resistance in vivo biofilm disruption therapy becomes real, the need for revision surgery would greatly diminish.
The launch of the emerging therapies is expected to significantly impact Prosthetic Joint Infection treatment scenario in the upcoming years:-Drugs covered1. Sodium Fusidate2. TNP-20923. PLG0206And many others
The key players in Prosthetic Joint Infection market are:1. Arrevus2. TenNor Therapeutics3. PeptilogicsAnd many others
Table of contents1. Key Insights2. Organizations3. Executive summary4. Prosthetic Joint Infection Epidemiology and Market Methodology5. Prosthetic Joint Infection Market Overview at a Glance6. Overview7. PJI Epidemiology and Patient Population8. Country Wise-Epidemiology of Prosthetic Joint Infection8.1. Country Wise-Epidemiology of Prosthetic Joint Infection8.2. United States8.3. EU5 Countries8.4. Germany8.5. France8.6. Italy8.7. Spain8.8. UK8.9. Japan8.10.China9. Prosthetic Joint Infection Treatment10. Unmet Needs11. Prosthetic Joint Infection Emerging Therapies11.1.Key Cross Competition11.2.Sodium Fusidate: Arrevus11.3.TNP-2092: TenNor Therapeutics11.4.PLG0206: Peptilogics11.5.Other Potential Therapies12. Prosthetic Joint Infection 7 Major Market + China Analysis13. Seven Major Market Outlook13.1.United States Market Size13.2.Germany13.3.France13.4.Italy13.5.Spain13.6.United Kingdom13.7.Japan13.8.China14. Market Drivers15. Market Barriers16. Reimbursement policies17. SWOT18. Case Study19. KOL Views20. Bibliography21. Appendix22. DelveInsight Capabilities23. Disclaimer24. About DelveInsight
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